Background Financial relationships between physicians and industry are extensive and public reporting of industry payments to physicians is now occurring. Our objectives were to describe physician recipients of large total payments from these seven companies, and to examine discrepancies between these payments and conflict of interest (COI) disclosures in authors’ concurrent publications. Methods The investigative journalism organization, ProPublica, compiled the Dollars for Docs database of payments to individuals from publically available data from seven US pharmaceutical companies during the period 2009 (...) to 2010. We examined the cohort of 373 physicians in this database who each received USD $100,000 or more in the reporting period 2009 to 2010. Results These physicians received a total of $52,600,624 during this period (mean payment per physician $141,020). The predominant specialties were internal medicine and psychiatry. 147 of these physicians authored a total of 134 publications in the first quarter of 2011 and 77% (103) of these publications provided a COI disclosure. 69% of the 103 publications did not contain disclosures of the payment listed in the Dollars for Docs database. Conclusions With increased public reporting of industry payments to physicians, it is apparent that large sums are being paid for services such as consulting and peer education. In over two-thirds of publications where COI disclosures were provided, the disclosures by physician authors did not include industry payments that were documented in the Dollars for Docs database. (shrink)

Much new global genetic research employs whole genome sequencing, which provides researchers with large amounts of data. The quantity of data has led to the generation and discovery of more incidental or secondary findings and to vigorous theoretical discussions about the ethical obligations that follow from these incidental findings. After a decade of debate in the genetic research community, there is a growing consensus that researchers should, at the very least, offer to return incidental findings that provide high‐impact, medically relevant (...) information, when it is not unduly burdensome to the research enterprise to do so. Much as genetic research has been limited to U.S. and European settings, the incidental findings debate has primarily focused on research conducted in high‐income countries. In a 2015 paper, Alberto Ortiz‐Osorno, Linda Ehler, and Judith Brooks note salient differences between the circumstances of research participants in low‐ and high‐resource settings that alter the analysis of when and why incidental findings should be offered to research participants. In this article, we expand on their analysis and present a framework for thinking about how investigators’ obligations to return genomic data might change in low‐resource settings, particularly in settings where participants do not have access to the medical care needed to treat, assess, or monitor incidental findings that are actionable in settings with plentiful resources. (shrink)

The recent Common Rule revision process took almost a decade and the resulting changes are fairly modest, particularly when compared to the ambitious ideas proposed in the advance notice of proposed rulemaking and notice of proposed rulemaking. Furthermore, the revision process did not even attempt to tackle any of the Common Rule subparts pertaining to vulnerable populations where commentators think the rules unduly restrict important research. We believe that this was a missed opportunity to make desirable changes, and that given (...) the usual process the next opportunity to revisit the Common Rule is unacceptably remote. In this article, we argue that the Common Rule should be regularly reassessed, with a mechanism for making substantive changes. Drawing on lessons learned from the recent revision process, we make recommendations about ways to structure future attempts to maximize the ability to make timely and necessary changes. (shrink)

Historically, entities with a vested interest in a product that critics have suggested is harmful have consistently used research to back their claims that the product is safe. Prominent examples are: tobacco, lead, bisphenol A, and atrazine. Research literature indicates that about 80–90% of studies with industry affiliation found no harm from the product, while only about 10–20% of studies without industry affiliation found no harm. In parallel to other historical debates, recent studies examining a possible relationship between mercury exposure (...) and autism spectrum disorder show a similar dichotomy. Studies sponsored and supported by industry or entities with an apparent conflict of interest have most often shown no evidence of harm or no “consistent” evidence of harm, while studies without such affiliations report positive evidence of a Hg/autism association. The potentially causal relationship between Hg exposure and ASD differs from other toxic products since there is a broad coalition of entities for whom a conflict of interest arises. These include influential governmental public health entities, the pharmaceutical industry, and even the coal burning industry. This review includes a systematic literature search of original studies on the potential relationship between Hg and ASD from 1999 to August 2015, finding that of the studies with public health and/or industry affiliation, 86% reported no relationship between Hg and ASD. However, among studies without public health and/or industry affiliation, only 21% find no relationship between Hg and ASD. The discrepancy in these results suggests a bias indicative of a conflict of interest. (shrink)

Historically, entities with a vested interest in a product that critics have suggested is harmful have consistently used research to back their claims that the product is safe. Prominent examples are: tobacco, lead, bisphenol A, and atrazine. Research literature indicates that about 80–90 % of studies with industry affiliation found no harm from the product, while only about 10–20 % of studies without industry affiliation found no harm. In parallel to other historical debates, recent studies examining a possible relationship between (...) mercury exposure and autism spectrum disorder show a similar dichotomy. Studies sponsored and supported by industry or entities with an apparent conflict of interest have most often shown no evidence of harm or no “consistent” evidence of harm, while studies without such affiliations report positive evidence of a Hg/autism association. The potentially causal relationship between Hg exposure and ASD differs from other toxic products since there is a broad coalition of entities for whom a conflict of interest arises. These include influential governmental public health entities, the pharmaceutical industry, and even the coal burning industry. This review includes a systematic literature search of original studies on the potential relationship between Hg and ASD from 1999 to date, finding that of the studies with public health and/or industry affiliation, 86 % reported no relationship between Hg and ASD. However, among studies without public health and/or industry affiliation, only 19 % find no relationship between Hg and ASD. The discrepancy in these results suggests a bias indicative of a conflict of interest. (shrink)

Historically, entities with a vested interest in a product that critics have suggested is harmful have consistently used research to back their claims that the product is safe. Prominent examples are: tobacco, lead, bisphenol A, and atrazine. Research literature indicates that about 80–90% of studies with industry affiliation found no harm from the product, while only about 10–20% of studies without industry affiliation found no harm. In parallel to other historical debates, recent studies examining a possible relationship between mercury exposure (...) and autism spectrum disorder show a similar dichotomy. Studies sponsored and supported by industry or entities with an apparent conflict of interest have most often shown no evidence of harm or no “consistent” evidence of harm, while studies without such affiliations report positive evidence of a Hg/autism association. The potentially causal relationship between Hg exposure and ASD differs from other toxic products since there is a broad coalition of entities for whom a conflict of interest arises. These include influential governmental public health entities, the pharmaceutical industry, and even the coal burning industry. This review includes a systematic literature search of original studies on the potential relationship between Hg and ASD from 1999 to August 2015, finding that of the studies with public health and/or industry affiliation, 86% reported no relationship between Hg and ASD. However, among studies without public health and/or industry affiliation, only 21% find no relationship between Hg and ASD. The discrepancy in these results suggests a bias indicative of a conflict of interest. (shrink)

The information theoretic principle of rational adaptation predicts that individuals with aphasia adapt to their language impairments by relying more heavily on comparatively unimpaired non-linguistic knowledge to communicate. This prediction was examined by assessing the extent to which adults with chronic aphasia due to left-hemisphere stroke rely more on conceptual rather than lexical information during verb retrieval, as compared to age-matched neurotypical controls. A primed verb naming task examined the degree of facilitation each participant group received from either conceptual event-related (...) or lexical collocate cues, compared to unrelated baseline cues. The results provide evidence that adults with aphasia received amplified facilitation from conceptual cues compared to controls, whereas healthy controls received greater facilitation from lexical cues. This indicates that adaptation to alternative and relatively unimpaired information may facilitate successful word retrieval in aphasia. Implications for models of rational adaptation and clinical neurorehabilitation are discussed. (shrink)

In her groundbreaking text Epistemic Injustice, Miranda Fricker evaluates types of harms incurred by individuals undergoing unrecognized and inarticulable oppression. At issue in epistemic and hermeneutic injustice are prejudicial comportments to and evaluations of reality. In the following, I focus on hermeneutic and epistemic injustice in relation to the formation of intellectual and ethical virtues. When reading Fricker and Hans-Georg Gadamer’s hermeneutics together, there is a clear pathway to improve ethical development. In particular, ethical development ought to cultivate the proper (...) virtues that promote understanding. Gadamer’s emphasis on the qualities of a researcher and the epistemic virtues that Fricker highlights reveal an educative path for addressing injustice. In other words, cultivating these virtues counteracts injustice wherein recognition and articulation of reality is challenged or at issue. (shrink)

The enforcement of racial segregation during apartheid was aimed not only at regulating public spaces, residential areas and the workforce, but also at shaping the subjectivities of individuals who were socialised to see themselves through the lens of a white racial hierarchy. The ideology of white supremacy and superiority that informed apartheid policy was largely justified using Christonormative epistemologies that sought to legitimate the racial hierarchy as having basis in Holy Scripture and as an extension of God’s will. At the (...) same time, apartheid policy fragmented religious communities, entrenching race as a central component of spiritual subjectivities. Twenty years after the end of apartheid, the legacy of apartheid continues to shape the lives and opportunities of all people living in South Africa, despite many gains made in working towards a non-racial, non-sexist democracy. While much scholarly attention has been paid to postapartheid contexts of work, residency and recreation, relatively little attention has been paid to spaces of worship. This is surprising, given that religious belief and practice are widespread in South Africa in the first instance, and that Christian belief, in particular, was so central to the social imaginary of apartheid, in the second. Thus, in efforts to transform society and advance social justice, it is imperative to consider diversity, difference and otherness from the perspective of, and in relation to, contemporary religious communities and contexts. This article will consider some of the factors shaping dynamics of diversity and difference within the context of religious communities in South Africa, over 20 years into democracy. (shrink)

We examine how the shift to remote work altered responsibilities for domestic labor among partnered couples and single parents. The study draws on data from a nationally representative survey of 2,200 US adults, including 478 partnered parents and 151 single parents, in April 2020. The closing of schools and child care centers significantly increased demands on working parents in the United States, and in many circumstances reinforced an unequal domestic division of labor.

Previous research on cross-situational word learning has demonstrated that learners are able to reduce ambiguity in mapping words to referents by tracking co-occurrence probabilities across learning events. In the current experiments, we examined whether learners are able to retain mappings over time. The results revealed that learners are able to retain mappings for up to 1 week later. However, there were interactions between the amount of retention and the different learning conditions. Interestingly, the strongest retention was associated with a learning (...) condition that engendered retrieval dynamics that initially challenged the learner but eventually led to more successful retrieval toward the end of learning. The ease/difficulty of retrieval is a critical process underlying cross-situational word learning and is a powerful example of how learning dynamics affect long-term learning outcomes. (shrink)

Hortense Spillers ends “Mama's Baby, Papa's Maybe” with a provocative suggestion: “Actually claiming the monstrosity … ‘Sapphire’ might rewrite after all a radically different text for female empowerment.” In this article, I knead the material, representational, and performative powers operating through conceptually separate and yet deeply entangled contested terrains: the “real,” or the scene of “actual mutilation,” whose high crimes against the flesh coincide with the construction of the “symbolic.” Through Baradian performativity, I read Spillers's theorization on the name as (...) an event wherein proprietary relationships, which necessarily oscillate between material/signification binaries, are called forth in historical terrain in the moment of racial address. Paying close attention to her grammar, the first half of this article tracks Spillers's movement through an undercurrent of American historical mythology that, as she demonstrates, misnames the black mother. The rest of this article then takes up to what extent certain “mocking doubles”—minstrel and/or monstrous tropes resuscitated but not redeemed or even necessarily renamed—might agitate their way toward new texts for female empowerment and the cultivation of the black mother's power to “name.”. (shrink)

Contestations over the rights of sexual minorities and gender-nonconforming people in Africa are profoundly shaped by two discourses that both emerge from polarized domestic political debates in the United States: a human rights–centered discourse of “LGBT*I” identity politics that promotes visibility and equal protections and privileges for lesbian, gay, bisexual, trans*, and intersex individuals; and a Christonormative “family values” agenda that promotes the heterosexual nuclear family as the foundation of civilization. Analysis considers these contemporary discourses in relation to entangled colonial (...) constructions of white supremacy and heteropatriarchy used to justify the conquest and exploitation of Africa. This article takes particular interest in the power relations that are constituted through these discourses so as to uncover the underlying interests at stake within them. Through consultation with critiques advanced within critical race and critical queer theory, and critical philosophical arguments on the epistemic dimensions of racialized, sexed, and gendered oppressions, it is argued that these discourses advance U.S. hegemonic interests and reinscribe Western hegemony. It is concluded that struggles for equality among sexual minorities and gender-nonconforming people must be approached as part-and-parcel of decolonial struggles to dismantle white supremacist and Western structures of oppression. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 8.1 (2003) 143-150 [Access article in PDF] Species Nova [To See Anew]Art as Ecology David Haley Looking Back From space, looking back at earth, we may see three key issues: the accelerating increase of the human species, the accelerating decrease of other species, and the accelerating effects of climate change. We might ask, how are we to cope with these changes creatively?That our societies (...) tend to value economics over ecology, and monoculture and agro-industry over diversity and permaculture, is certainly worthy of ethical attention. Here I want to invoke a call for integrating art as a necessary contribution to ecological intervention. I consider how artists may engage uncertainty, and how art may be used to develop new ways of seeing and "drawing." This is art for evolutionary survival, not commodification. Art that practices care, shared responsibility, and diversity in the pursuit of eco-centric cultures. Although this paper mainly references visual art forms, this should not be taken to exclude others. Here I am primarily concerned with identifying some of the possible forms of ecological or eco-art. This is art practiced by artist and inventors in the manner of the archetype of Daedalus and worthy of the name implied by the root of the word art. Rt, an ancient term from the Rg Vedas, refers to the virtuous, continuing creation of the cosmos. [End Page 143] Seeing is Believing/ Uncertainty in View The suffix species nova is ascribed by scientists to a new bacterium species, prior to the confirmation of its existence in the appropriate academic journals. The word species means "to look" and "a class of things, living organisms capable of exchanging genes, classified as a taxonomic rank below a genus and denoted by a Latin binomial." It also refers to "the visible form of each of the elements of consecrated bread and wine in the Eucharist." Nova refers to the mistaken sighting of a new star, a flash of brightness that quickly dims. Something novel is a new kind of nature, something strange or previously unknown, and novelty refers to invention. Species nova: two words that evoke ideas about innovations of visual experience and belief.I use the phrase to denote the potential for understanding a new order and evolutionary change—"to see anew." I am also aware that species nova could mean a mistaken religious experience, or a class of living things that flashes brightly and quickly dims. Uncertainty is embedded in the richness of meanings.It is ten years since the Earth Summit in Rio popularized the notion of sustainable development and introduced Agenda 21 as a strategy to achieve it. Sadly, culture and art, two of the systems that define humanity, were not mentioned among the necessary tools for building a better future.But what is sustainable development? Is it about conservation, restoration, or regeneration? Will it stop global warming and feed the poor, or is it like candyfloss—a confection of transient comfort, with no real meaning? Has it become a corrupt cultural construct, an anthropocentric myth in the vain pursuit of hope?Recently the Intergovernmental Panel on Climate Change confirmed that "most of the warming observed over the past 50 years is attributable to human activities." However, the projections and models that have been developed for policy makers to envisage climate change scenarios demonstrate the limits of our ability to understand the situation, let alone adapt to it. A recent review in Nature, comparing two twenty-year forecasts ironically concluded: Uncertainties therefore remain that are beyond the statistical uncertainties described in the two papers. But both sets of authors point out that the upper bound on the potential warming for 2100 may well be [End Page 144] above the IPCC figure of 5.8K under 'heavy emissions' scenarios. So policy-makers should not discount the possibility of a very warm climate considering long-range policy options. (Funnel 2001, 5) A subsequent article in Nature's Climate Change Review reveals even more concern about communicating scientific uncertainty, because models that simulate long-term climate changes cannot be tested using real... (shrink)

For over 20 years, the Schmid Training Course (STC) has offered unique opportunities for marine biology students from European universities to learn about marine model organisms. While the topics of the course have continuously changed over the years with the advent of new research techniques and discoveries, the pedagogical approach has remained largely the same – a combination of lectures, lab practicals, and field excursions. Several life science researchers, who have taught in the STC for many years, sought to bring (...) the course's pedagogical approach into the 21st century, and with the support of Erasmus+ Programme of the European Community funding, the Digital Marine project was developed. Digital Marine began in 2018 as an international partnership between the six research centers from which the STC instructors hail, and its main objective was to introduce a flipped, blended approach to learning and teaching with respect to established and emerging marine biological model systems. The Digital Marine platform, which covers 12 marine model organisms, is now publicly available. (shrink)

The moral/conventional task has been widely used to study the emergence of moral understanding in children and to explore the deficits in moral understanding in clinical populations. Previous studies have indicated that moral transgressions, particularly those in which a victim is harmed, evoke a signature pattern of responses in the moral/conventional task: they are judged to be serious, generalizable and not authority dependent. Moreover, this signature pattern is held to be pan‐cultural and to emerge early in development. However, almost all (...) the evidence for these claims comes from studies using harmful transgressions of the sort that primary school children might commit in the schoolyard. In a study conducted on the Internet, we used a much wider range of harm transgressions, and found that they do not evoke the signature pattern of responses found in studies using only schoolyard transgressions. Paralleling other recent work, our study provides preliminary grounds for skepticism regarding many conclusions drawn from earlier research using the moral/conventional task. (shrink)

Cross‐situational word learning (XSWL) tasks present multiple words and candidate referents within a learning trial such that word–referent pairings can be inferred only across trials. Adults encode fine phonological detail when two words and candidate referents are presented in each learning trial (2 × 2 scenario; Escudero, Mulak, & Vlach, ). To test the relationship between XSWL task difficulty and phonological encoding, we examined XSWL of words differing by one vowel or consonant across degrees of within‐learning trial ambiguity (1 × (...) 1 to 4 × 4). Word identification was assessed alongside three distractors. Adults finely encoded words via XSWL: Learning occurred in all conditions, though accuracy decreased across the 1 × 1 to 3 × 3 conditions. Accuracy was highest for the 1 × 1 condition, suggesting fast‐mapping is a stronger learning strategy here. Accuracy was higher for consonant than vowel set targets, and having more distractors from the same set mitigated identification of vowel set targets only, suggesting possible stronger encoding of consonants than vowels. (shrink)

Voices on the political right have long claimed that the welfare state ought to be kept small, and that charities can take over many of the tasks involved in helping those at the bottom of society. The arguments in favor of this claim are controversial, but even if they are accepted at face value the policy proposal remains problematic. For the proposal presupposes that charities would, in fact, be able to raise enough money to provide adequate help to those in (...) need, and therefore assumes that charities are able to very significantly increase the number and/or size of donations they receive. We argue that there are good reasons for doubting that charities will be able to do this. Our argument turns on the fact that the most powerful strategy for eliciting donations—namely, allowing donors to use their donation to signal their pro-sociality—has an inbuilt upper limit. If too much emphasis is placed on the signaling opportunities donating to charity provides, donating no longer functions as an effective signal and the motivation to donate declines. (shrink)

The colonization of a new planet will inevitably bring about new bioethical issues. One is the possibility of pregnancy during the mission. During the journey to the target planet or moon, and for the first couple of years before a colony has been established and the colony has been accommodated for children, a pregnancy would jeopardize the safety of the crew and the wellbeing of the child. The principal concern with a pregnancy during an interplanetary mission is that it could (...) put the entire crew in danger. Resources such as air, food, and medical supplies will be limited and calculated to keep the crew members alive. We explore the bioethical concerns of near-future space travel. (shrink)

In Eckhart, Heidegger, and the Imperative of Releasement, Ian Alexander Moore investigates Martin Heidegger’s use of releasement. Moore argues that this conceptual development was greatly influenced by Meister Eckhart’s thought. In addition to their shared use of releasement, Moore suggests, both Heidegger and Eckhart share similar philosophical strategies. The task of Moore’s monograph is to illuminate how releasement functions in Heidegger’s work and to argue that Eckhart was one of Heidegger’s central influences. This review examines Moore’s method for assessing the (...) function of releasement in Heidegger and Eckhart’s thought, while noting the distinctive and compelling aspects of this monograph. (shrink)

Time is a neglected subject in recent, especially analytically minded reflections on the good life. The article highlights the fundamental role of time and temporality for an adequate understanding of the good life. Time functions both as an external factor with which we have to reckon in our practical deliberations and as an internal structure of living our lives. It is argued that striving for a good life also means striving for being in harmony with the time of one's life. (...) The exploration of this idea allows to link analytical with phenomenological approaches to time and good life. (shrink)

Food producers have answered increasing consumer demand for transparency through disclosure of information on food labels. Food safety labels act as a signal to consumers that certain products may pose a risk to human health. These labels are based on developments in microbiology and/or represent a required response to foodborne illness outbreaks. However, the scope of the risk posed by product consumption, as well as who is most vulnerable to harm, varies based on the ethical reasoning underlying the presence of (...) the label on the package. This paper applies Thompson (International Journal of Food Science and Technology 36: 833–843, 2001)‘s theory on two contrasting ethical approaches to risk communication – choice optimization and informed consent – to evaluate the four most common food safety labels in the US: i) unpasteurized juice warnings; ii) egg carton safe handling instructions; iii) consumer advisories on restaurant menus; and iv) date labeling. While the choice optimization approach dictates that food safety labels are a necessary tool to equip consumers with specific information that will promote public health (i.e., egg carton safe handling instructions), informed consent obliges producers to disclose all relevant risk information so consumers can choose one product or another based on its adherence to individual values (e.g., unpasteurized juice; undercooked animal products). This paper finds that the US food safety regime represents a blending of these two ethical foundations, leading to substantial variation in risk consumer tolerance and/or aversion. One effect of the intermingling of these two ethical approaches is choice overload among consumers for newer food safety labels (e.g., date labels). This paper concludes with a discussion of policy prioritization in the context of an increasingly crowded food label marketplace. (shrink)

Machery proposes that the construct of detracts from research progress. However, ignoring development also detracts from research progress. Developmental research has advanced our understanding of how concepts are acquired and thus is essential to a complete theory. We propose a framework that both accounts for development and holds great promise as a new direction for thinking about concepts.

This chapter contains sections titled: Introduction Is ‘subject appropriation’ a misnomer? Subject appropriation and misrepresentation Cultural Appropriation and Assimilation Harm and Accurate Representation Privacy Authenticity and Subject Appropriation Envoy Conclusion References.

Management and organization researchers are being called to conduct research that is more caring, yet the concept of care and how to practice it within the profession is undertheorized. Adopting a feminist epistemology and methodology, we develop the concept of care by weaving the personal, ethical, and political into the research process. First, we reflect critically on how aspects of care—attentiveness, responsibility, competence, and responsiveness (Tronto, Moral boundaries: a political argument for an ethic of care, Routledge, 1993; Tronto, Caring democracy: (...) markets, equality, and justice, New York University Press, 2013)—unfolded in our personal research experiences, and secondly, we conduct a review of articles published in management and organization studies and analyse expressed or concealed conceptions of care in scholars’ accounts of research purpose and ethics. We find three ethical sensibilities at the heart of enacting care: encountering the ‘other’, interpreting roles and responsibilities, and deliberating needs and resources. We contribute to a feminist research ethics by highlighting issues related to care that are concealed in dominant ethos guiding management and organization research. Further, we develop methodological insights for implementing an ethic of care as an alternative ethical standpoint in business research ethics. Finally, we provide suggestions for how to embed more care within research ethics practices in academic institutions. (shrink)

Performance measurement has far-reaching implications for not-for-profit organizations because it serves to legitimize, attract resources, and preserve expectations of stakeholders. However, the existing theory and practice of not-for-profit performance measurement have fallen short, due in part, to an overuse of profit-oriented philosophies. Therefore, we examine not-for-profit performance measurement by utilizing Marques’ “five spiritual practices of Buddhism.” Marques’ spiritual practices—a pro-scientific philosophy, greater personal responsibility, healthy detachment, collaboration, and embracing a wholesome view—are the foundation of our research design. Responses from senior (...) not-for-profit practitioners support the linkages between spiritual practices and not-for-profit performance measurement. We identify three essential performance measurement principles and elaborate on their capacity to generate awareness, higher meaning, and connectedness within not-for-profits. (shrink)